What is Rejuran?
Rejuran is an injectable skin treatment made from polynucleotides (PN), purified DNA fragments derived from salmon, which stimulate the skin’s own repair processes and collagen production. Rather than adding volume or filling lines, it works by improving the quality and resilience of the skin itself.
Developed in South Korea, where it has been widely used for years, Rejuran became available in Australia in 2023 and is offered at VCI in Melbourne under doctor-led care. It’s often described as a skin booster, and suits people wanting healthier, better-quality skin rather than a change to their features.
How Rejuran works
Rejuran works by delivering polynucleotides from purified salmon DNA into the dermis through a series of small injections. Once in the skin, these polynucleotides activate fibroblasts, the cells responsible for producing collagen, while calming inflammation and supporting the skin’s natural wound-healing processes. Over the following weeks, this rebuilds collagen and elastin from within, gradually improving firmness, hydration, and texture.
Because it works with your skin’s own biology, the change is gradual and natural rather than immediate. A typical course is three sessions spaced two to three weeks apart, with maintenance every six to twelve months to sustain the results.
How Rejuran compares with other skin treatments
Rejuran sits alongside several other skin-quality treatments, and the doctors choose between them based on your skin. Rejuran regenerates skin quality by stimulating repair from within, bio-remodelling treatments focus on deep hydration, collagen stimulating treatments restore structure and volume, and laser resurfacing works on the skin’s surface.
They’re complementary rather than competing, and are often combined in a plan. Which is right for you depends on what your skin needs, worked out at your consultation.
What results can you expect from Rejuran?
Rejuran results build gradually over a course of treatment rather than appearing all at once. As new collagen forms, skin looks fresher, smoother, and more even, with improvement continuing for weeks after each session.
Most people notice better skin quality, softer fine lines, and improved texture and hydration developing over the weeks following each session. A typical course is three sessions spaced two to three weeks apart, with results continuing to build after the final session and lasting around six to twelve months when maintained. Because Rejuran works with your skin’s own repair processes, the change is natural and cumulative rather than sudden.
Individual results vary. A consultation is required to determine treatment suitability.
Who is Rejuran for?
Rejuran suits adults who are noticing fine lines, uneven tone or texture, dullness, or early loss of elasticity, and anyone wanting better skin quality rather than added volume. Because it works by improving the skin itself, it’s well suited to people who want a subtle, cumulative improvement rather than a dramatic or immediate change.
It suits all skin types, and is often chosen by those who feel their skin looks tired or lacklustre despite a good skincare routine. Whether Rejuran is right for you is confirmed at your consultation, where the doctors assess your skin and your goals.
Under eyes
The delicate skin under the eyes is one of the most common reasons people choose Rejuran. The lighter formulation designed for this area treats fine lines, crepiness, and the tired, shadowed look that comes from thin, crepey under-eye skin, where volume-based approaches often aren’t the right answer. It works by improving the quality and resilience of the skin itself, for a fresher, less tired appearance.
Fine lines and skin texture
Across the rest of the face, Rejuran is used to improve early fine lines, rough or uneven texture, enlarged-pore-prone skin, and the texture changes left after breakouts. Rather than filling lines, it repairs and strengthens the skin from within, improving overall quality and smoothness over the course of treatment.
Who it’s not for
Rejuran isn’t suitable for everyone. It’s deferred during pregnancy and breastfeeding, with an active skin infection or inflammation at the treatment area, and with certain autoimmune or blood disorders or recent procedures in the same area. If Rejuran isn’t the right treatment for you, or your expectations aren’t realistic, the doctors will say so honestly and suggest what might suit you better.
Benefits of
Rejuran injections
- Stimulates the skin’s own collagen and elastin production
- Improves hydration and strengthens the skin barrier
- Softens fine lines and improves overall texture
- Suits delicate areas like under the eyes, using the lighter formulation
- Gradual, natural-looking improvement rather than sudden change
How it works
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Book a consultation
Cosmetic treatments require an initial consultation, offered with no obligation to proceed, so you can make an informed decision about your options. Your doctor assesses your skin and concerns, discusses your goals, and creates a personalised Rejuran treatment plan.
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Pre-treatment care
If preparation is required, you receive clear pre-treatment instructions to support a safe treatment and a smooth recovery.
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Your treatment appointment
Your Rejuran treatment is performed with approved products by VCI’s clinical team, with safe, evidence-based care in a comfortable, professional environment.
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Post-treatment care
You receive specific aftercare instructions to support your recovery, and the team is available to answer any questions during this time.
What’s included in your Rejuran treatment at VCI
We believe in being clear about what your treatment includes, so there are no surprises. Your Rejuran treatment at VCI includes:
- A medical consultation with a doctor, including a skin examination, VISIA skin analysis, and clinical photography
- A personalised treatment plan and a full consent process
- Numbing cream applied before treatment for your comfort
- The Rejuran injections, performed by VCI’s clinical team
- A review appointment two to four weeks after your treatment
It’s also worth being clear about what sits outside a single session. Rejuran works best as a course, typically three sessions, and ongoing maintenance sessions and any supporting skincare are planned separately. We’ll set all of this out clearly at your consultation, so you know what’s involved and what it costs before you decide.
How much does Rejuran cost in Melbourne?
Rejuran at VCI starts from [$X] per session, with a typical three-session course from [$X].
Rejuran is priced per syringe, so the total depends on the areas treated, the formulation used (full face, or the lighter formulation for under the eyes), and the number of sessions in your course. Because Rejuran works best as a course rather than a single treatment, it’s worth thinking about the cost across the full plan rather than per session alone.
At your consultation, we’ll assess your skin, recommend the right plan, and give you a clear, itemised breakdown before you decide, so you know exactly what’s involved with no pressure to proceed.
Our medical team for Rejuran
Rejuran at VCI is consulted on and performed by our medical team at our Templestowe Lower clinic.
VCI was founded and is led by Dr Gavin Chan (MBBS, registration MED0001175745), who has practised cosmetic medicine since 2005, alongside our multi-disciplinary team of cosmetic doctors and registered nurses. Every Rejuran treatment begins with a doctor-led consultation, so your plan is guided by genuine medical assessment rather than a sales conversation.
This doctor-led approach is central to how we work, and it’s what allows us to give you honest advice about whether Rejuran is the right treatment for your skin.
“Good cosmetic medicine starts with good information.”
Preparation and what to expect
Here’s what’s involved before, during, and after your Rejuran treatment, so you know what to expect at each stage.
Before
Arrive with clean, makeup-free skin. Where medically appropriate, you may be advised to avoid blood-thinning medications and supplements beforehand to reduce bruising [writer to confirm specifics with VCI]. Before treatment, we take clinical photography and a VISIA scan, and apply numbing cream for your comfort.
During
Rejuran is delivered through a series of small injections across the treatment area. The appointment usually takes 30 to 60 minutes including numbing time. Most people find it involves mild stinging rather than pain, and the numbing cream helps keep you comfortable throughout.
After
You may notice small bumps at the injection points, which usually settle within about 24 hours, along with possible mild bruising or swelling. We recommend avoiding strenuous exercise, sun exposure, and active skincare for a short period afterwards [writer to confirm timeframes with VCI]. Visible improvement builds gradually over the course of treatment, and you’ll have a review appointment two to four weeks later.
Results appear gradually as collagen rebuilds, typically becoming noticeable from a few weeks after your second session, and last around six to twelve months with maintenance.
How much does Rejuran cost in Melbourne?
Rejuran at VCI starts from [$X] per session, with a typical three-session course from [$X]. Because it’s priced per syringe, the total depends on the areas treated, the formulation used, and the number of sessions in your plan. You’ll get a clear, itemised breakdown at your consultation before you decide anything.
How many Rejuran sessions will I need?
Most people have a course of three sessions, spaced two to three weeks apart, for the fullest result. Because Rejuran works by gradually rebuilding collagen, a course allows the improvement to build over time. Maintenance sessions every six to twelve months help sustain the results. Your exact plan is confirmed at your consultation.
How long does Rejuran last?
Results from a full course of Rejuran typically last around six to twelve months. Because Rejuran improves the skin’s own quality rather than adding a temporary filler, the improvement is gradual and natural, and maintenance sessions once or twice a year help keep your skin looking its best over time.
What is the downtime after Rejuran?
Downtime is minimal. You may have small bumps at the injection points that settle within about 24 hours, and some people experience mild bruising or swelling for a day or two. Most people return to their normal routine straight away, avoiding strenuous exercise and active skincare briefly afterwards.
Does Rejuran hurt?
Most people find Rejuran involves mild stinging rather than pain. Numbing cream is applied before treatment to keep you comfortable, and the injections themselves are small and quick. Any discomfort is brief and settles once the treatment is done.
Is Rejuran safe, and what are the side effects?
Rejuran has a strong safety profile and is well tolerated when performed by trained clinicians. Because it’s derived from purified salmon DNA, it’s biocompatible and low-risk. The most common side effects are temporary and mild: small bumps, minor bruising, redness, or swelling at the injection sites, which settle within a few days.
When will I see results from Rejuran?
Results appear gradually as your skin rebuilds collagen, rather than immediately. Most people begin to notice improved skin quality and texture from a few weeks after their second session, with the full result developing over the course of treatment.
Can Rejuran be combined with other treatments?
Yes. Rejuran is often combined with other skin treatments, such as laser or skin-quality treatments, as part of a broader plan, and the doctors will advise what works well together. Combining treatments is planned carefully at your consultation to suit your skin and goals.
